ABSTRACT
In this work, we evaluated computed tomography (CT) results of the chest in patients with COVID-19 pneumonia. Preliminary articles were searched in the scientific databases PubMed, MEDLINE, Embase, EBSCO between 2019 to 2021. Fixed-effect model for meta-analysis using the inverse-variance method calculates effect size with 95% confidence interval (CI). Data analysis was performed using STATA software version 16. Overall effect size of Ground glass opacities (GGO) in patients with coronavirus disease 2019 (COVID-19) was 2.30 (ES, 95% CI 1.56, 3.3). Ground-glass opacity was a typical finding in COVID-19 pneumonia on CT;its incidence was about 80%. Abnormal CT in patients with COVID-19 was 2.69 (ES, 95% CI 2.52, 2.87). Ground-glass opacity is the foremost typical CT scan result in coronavirus disease 2019, and lung involvement is more common in bilateral and lower lung areas.
ABSTRACT
COVID – 19 is a contagious disease caused by severe acute respiratory syndrome (SARS-CoV2). The rate at which COVID – 19-virus spread from epidemic to pandemic within a short period is quite alarming. As of July 2020, the Dashboard of the World Health Organization (WHO) recorded over 15 million COVID – 19 cases across 213 countries, with mortality of over 620,000. The governments and healthcare agencies responsible for mitigating the virus's spread have adopted several strategies to end the pandemic. However, all hands were on deck to establish the standard treatment modalities of SARS-CoV-2 through inventing new drugs, vaccine candidates, or repurposing the existing medicines and robust diagnostic tools, in addition to other technological innovations. Therefore, nanotechnology’s employment would play a vital role in bringing multidisciplinary ways of developing affordable, reliable, and powerful tools for diagnosis, in addition to personal protection and effective medicines. Additionally, nanosensors' application would significantly aid the diagnoses of the COVID–19 even on asymptomatic patients, and thus would be an essential means for determining its prevalence. Likewise, nanoscale fibers can optimize personal equipment protection and allow their reusability for medical and economic benefits. Accordingly, the literature was intensively reviewed by searching for the combinations of the research keywords in the official scientific databases such as Science Direct, PubMed, and Google Scholar. Hence, this research highlighted the perspective contributions of nanotechnology in the war against the COVID-19 pandemic. Copyright © 2021 Shehu, Auwal, Musa, Mukhtar, Yusuf, Yau, Muhammad, Baba Dala, Sani, Ahmad and Islam.